Engineering a cancer-fighting virus

EurekAlert | January 29, 2019

An engineered virus kills cancer cells more effectively than another virus currently used in treatments, according to Hokkaido University researchers.
Hokkaido University researchers have engineered a virus that selectively targets and kills cancer cells. The virus, called dl355, has an even stronger anticancer effect than another engineered virus currently used in clinical practice, according to a study published in the journal Oncology Reports.
Molecular oncologist Fumihiro Higashino and colleagues deleted a gene involved in viral replication, called E4orf6, from a type of adenovirus. The team previously discovered that E4orf6 stabilizes a type of mRNA called ARE-mRNAs in the infected cells enabling viral replication.

Spotlight

Bridging the gap between engineers and geologists can be facilitated by using tools that can assist with cognitive tasks. In particular, infographics can be particularly useful. Infographics can serve a unique purpose in an online course or training program in that they both engage learners and provide a very handy mnemonic which assists in the storing and retrieving of information.

Spotlight

Bridging the gap between engineers and geologists can be facilitated by using tools that can assist with cognitive tasks. In particular, infographics can be particularly useful. Infographics can serve a unique purpose in an online course or training program in that they both engage learners and provide a very handy mnemonic which assists in the storing and retrieving of information.

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ENGINEERING TECH

AECOM secures positions on Transport for London engineering consultancy framework

AECOM | November 25, 2021

AECOM (NYSE: ACM), the world’s trusted infrastructure consulting firm, announced it has won places on over 30 Lots of the Transport for London (TfL) Engineering Consultancy Framework (ECF), including places on the strategic Multidisciplinary Engineering Services and Multidisciplinary Rail Engineering Services Lots. The four-year framework will be the primary means of accessing engineering consultancy services for TfL, the Greater London Authority, all 32 London borough councils and the City of London. “This important framework builds on our long-term relationship with TfL, expanding our scope of services and technical disciplines available to them,The framework enables us to bring our full breadth of diverse services to every project, supporting TfL as it continues to improve every journey for people who live and travel in London.” -Lara Poloni, AECOM’s president The new framework replaces the TfL Rail Engineering and Multidisciplinary Services frameworks and is expected to support the delivery of a range of projects and programs across all TfL infrastructure, including major station upgrades, surface works, oversite developments and line extensions. The framework Lots cover multidisciplinary engineering services, specialist engineering services, engineering architectural services, highways engineering and rail engineering. AECOM has worked with TfL since its inception across all transport modes and has supported the delivery of transformative programs such as Crossrail, Cycle Superhighways and Healthy Streets. Other current projects with TfL include DLR Thamesmead and Bakerloo Line Extension. About AECOM AECOM (NYSE: ACM) is the world’s trusted infrastructure consulting firm, delivering professional services throughout the project lifecycle – from planning, design and engineering to program and construction management. On projects spanning transportation, buildings, water, new energy and the environment, our public- and private-sector clients trust us to solve their most complex challenges. Our teams are driven by a common purpose to deliver a better world through our unrivaled technical expertise and innovation, a culture of equity, diversity and inclusion, and a commitment to environmental, social and governance priorities. AECOM is a Fortune 500 firm and its Professional Services business had revenue of $13.3 billion in fiscal year 2021. See how we are delivering sustainable legacies for generations to come at aecom.com and @AECOM.

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MARKET

Toyota Motor Corporation Australia Selects Cigniti Technologies as a Strategic Quality Engineering Partner

Cigniti | November 09, 2020

Cigniti Technologies, a global leader in independent quality engineering and software testing services, is now a strategic Quality Engineering panel vendor for Toyota Motor Corporation Australia (TMCA), a subsidiary of Toyota Motor Corporation, to help accelerate its Quality & Digital transformation journey over the next 3 years.Speaking on the occasion, Srikanth Chakkilam, CEO at Cigniti Technologies, said: “It is exciting and a proud moment for all of us at Cigniti to serve a leading automobile company. In this IOT enabled future of connected and autonomous vehicles, Technology will disrupt the entire automobile value chain. Software is going to greatly influence the future of the automobile industry. Digital transformation in the automobile industry will take place in the future across the value chain from the connected supply chain and manufacturing, to providing a virtual experience in the car buying process, Car Mobility as a Service, and autonomous driving. It is very important to ensure that high quality software will enhance the customer experience.”Cigniti has been working with Toyota Australia since 2017. This new agreement with Cigniti will assist Toyota in increasing its automation cadence by achieving test automation and non-functional testing goals across multiple digital platforms.

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DESIGN

AECOM to provide architecture and engineering services for Kennedy Space Center and other NASA facilities

AECOM | September 24, 2021

AECOM , the world’s trusted infrastructure consulting firm, today announced that it has been selected by the National Aeronautics and Space Administration (NASA) to provide architecture and engineering services as part of its Southeast Regional Architect and Engineering (SERAE) program. The indefinite delivery, indefinite quantity (IDIQ), multiple-award contract has a shared program ceiling of $300 million for its five-year term. Our relationship with NASA dates back over fifty years and we’re looking forward to building on that legacy through this integral work,As NASA has grown, evolved, and continued to push the boundaries of space exploration, AECOM has been there to support its globally impactful missions and cutting-edge operations. We’re immensely proud to be granted new opportunities with the administration that highlight our shared values of integrity, collaboration, and inclusion while maintaining a keen focus on the impacts we’re leaving on the world. -Karl Jensen, executive vice president AECOM’s National Governments business. AECOM’s work will focus on the rehabilitation, modernization, and development of new systems for facilities, utilities, and ground support at several prominent NASA locations across the United States. These include Kennedy Space Center in Florida; Johnson Space Center, Sonny Carter Training Facility, and Ellington Field in Texas; White Sands Test Facility in New Mexico; Marshall Space Flight Center in Alabama; Michoud Assembly Facility in Louisiana; Stennis Space Center in Mississippi; other NASA assets; and additional launch or landing sites worldwide. “From the Mercury and Gemini programs through today, AECOM has been honored to work alongside NASA on all of its facilities spanning the country. This new contract allows us to continue our successful and longstanding partnership,” said Sean Chiao, Chief Executive of AECOM’s global Buildings + Places business. “We’re excited to leverage our intimate knowledge of the administration’s enterprises and best practices to deliver unmatched professional services that advance NASA’s goal of leading an innovative and sustainable program of space exploration, scientific discovery, and aeronautics research to the next frontier.” Under the contract, AECOM will provide a wide range of architecture, civil, structural, mechanical, and electrical infrastructure services across all project phases, including planning and feasibility, permitting, preliminary engineering, final design, engineering services during construction, activation, and commissioning. These services include architectural design, field investigations and surveys, engineering and environmental reports, trade studies, design specifications, construction site inspections, and scheduling and cost estimating. About AECOM AECOM is the world’s trusted infrastructure consulting firm, delivering professional services throughout the project lifecycle – from planning, design and engineering to program and construction management. On projects spanning transportation, buildings, water, new energy and the environment, our public- and private-sector clients trust us to solve their most complex challenges. Our teams are driven by a common purpose to deliver a better world through our unrivaled technical expertise and innovation, a culture of equity, diversity and inclusion, and a commitment to environmental, social and governance priorities. AECOM is a Fortune 500 firm and its Professional Services business had revenue of $13.2 billion in fiscal year 2020. See how we are delivering sustainable legacies for generations to come at aecom.com and

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